Cherubism: A Case Report
نویسندگان
چکیده
Cherubism is a rare genetic disorder resulting in the replacement of mandible and sometimes maxilla with expansile cystic lesions. The usually presents childhood, eventual quiescence early adulthood. We report case cherubism involving both complicated by mass effect on nasal cavity left orbit. Pathologic features, clinical considerations, treatment are discussed. 
منابع مشابه
Cherubism: A Case Report
Cherubism, a pediatric disease, is a self limiting non-neoplastic autosomal dominant fibro-osseous disorder of jaws. It is a self limiting disease and rarely apparent before the age of two years. It occurs in children and predominantly in boys. It is characterized by clinical bilateral swelling of cheeks due to bony enlargement of jaws that give the patient a typical 'cherubic' look. Regression...
متن کاملCherubism--a case report.
Introduction: Cherubism is a rare, non neoplastic, fibroosseous disorder seen in children which is characterized by bilateral painless enlargement of the jaws giving a cherubic appearance to the patient. It is an autosomal dominant disorder but may occur sporadically as well. The treatment of cherubism is contentious. It is said that the disease regresses by itself and even after regression, ...
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Cherubism is a rare disorder with autosomal dominant inheritance. It is classified as a benign fibro-osseous lesions and may involve either facial bone. Its typical dentofacial deformities are caused by mutations in the SH3BP2 gene. The protein encoded by SH3BP2 had a significant role in the regulation of osteoblasts and osteoclasts. Accordingly with the radiological findings, differential diag...
متن کاملCherubism: a case report.
Cherubism is a familial benign fibro-osseous disease of the jaws. On radiography, the lesions exhibit bilateral multinuclear radiolucent areas. Histopathology reveals multinucleated giant cells in the background of proliferating fibrous connective tissue. Mutations in the SH3BP2 gene are identified as the cause of cherubism. A 12-year-old girl with prominence of the lower face was investigated....
متن کاملCherubism in siblings: a case report.
Cherubism is a non-neoplastic bone disease characterized by clinically evident bilateral, painless enlargements of the jaws that are said to give the patient a cherubic appearance. Cherubism may appear in solitary cases or in many members of the same family, often in multiple generations. On radiography, the lesions exhibit bilateral multilocular radiolucent areas. Histopathologic evaluation re...
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ژورنال
عنوان ژورنال: UCLA Radiological Sciences Proceedings
سال: 2023
ISSN: ['2766-8606']
DOI: https://doi.org/10.5070/rs43258724